Symptoms of Addison’s disease are not so specific in dogs. Moreover, even these vague symptoms vary over a period leading to a situation where dog owners are not even sure of its prevalence. Addison’s disease generally occurs due to autoimmune conditions.

Although it is not a conclusive diagnostic procedure, it is important to look for the level of primary ions of electrolytes like sodium and potassium. The proper amount and distribution of electrolytes in the body is essential for your dog’s health.

Final diagnosis of Addison’s disease, however, is done only after checking the response of the dog’s body to ACTH. ACTH is a hormone that is secreted by the anterior pituitary gland to stimulate the adrenal cortex to produce its own hormones.

Addison’s disease is basically a production disorder and is caused by an insufficiency of hormones secreted by the adrenal cortex. This is unlike canine Cushing’s disease, which is caused by excessive production of adrenal hormones. Addison’s disease is managed by giving supplemental hormones.

Aldosterone, a corticosteroid hormone produced by the adrenal glands that regulates salt (sodium and potassium) and water balance needs to be supplemented. This is achieved by administering a mineralocorticoid that influences the metabolism of sodium and potassium.

Prednisone is a synthetic corticosteroid used by many veterinarians to treat a wide variety of conditions in dogs including:

* Disorders of the central nervous system.
* Endocrinal disorders like Cushings disease and Addisons disease.
* Neoplastic conditions that is growth of tumors.
* Immune mediated diseases.
* Emergency situations like spinal chord trauma.
* Inflammation related respiratory and bowel disorders.

Side effects of prednisone depend directly on the quantum and duration of the drug administered. Short term use of prednisone is less likely to cause any damaging side effects. It is only when the dose reaches an immunosuppressive level when the side effects start causing concern.

Overdose of prednisone can cause suppression of normal adrenal functions, Cushing’s disease in dogs and destabilization of metabolism if withdrawn abruptly. Short term use can cause excessive urination abnormal hunger and an increase in the appetite for dogs. Prolonged use, even in recommended dosages may cause:

* Diarrhea.
* Gastrointestinal ulcers.
* Inflammation in the pancreas.
* Muscle degeneration.
* Vomiting.
* Weight gain.
* Diabetes.
* Behavioral changes.
* Skin and hair coat problems.