Pet Herbal Info Blog

posted by Tess on Apr 12

Cushing’s disease is a glandular disorder caused by excessive corticosteroids. The process of the production of these corticosteroids is such that:

* The pituitary gland produces a hormone called ACTH
* The ACTH stimulates the adrenalin glands
* The adrenalin gland produces corticosteroids
* A more than required amount of corticosteroid can cause Cushing’s disease, so it is also called hyperadrenocorticism (hyper-adreno-corticism).

The overproduction of corticosteroids which causes Cushing’s disease in dogs can occur due to two types of conditions. In 85% of the cases, the excessive production of ACTH is caused by a tumor in the pituitary gland that produces high levels of ACTH. This causes the adrenalin glands to make more than required levels of corticosteroids. Hyperadrenocorticism in a dog can also be caused by a corticosteroid-producing tumor in one or both of the adrenalin glands.

Cushing’s disease in dogs can also be caused by large doses of synthetic corticosteroids. These steroids may be administered for treating another ailment but in turn produce a side effect that results in Cushing’s disease.

Cushing’s disease generally occurs in dogs that are five years or older. It is more common in female dogs than in male dogs. Some breeds like Terriers, Poodles, and Dachshunds are more prone to Cushing’s disease for some inexplicable reason.

Cushing’s disease affects the overall health of the dog, since corticosteroids play an important role in a large number of body functions. Some of the symptoms of the disease are:

* A gradual but definite weakening of the ligaments
* Weight gain and a potbelly
* Degeneration of the skin leading to rashes and lumps
* Hair loss
* An increase in appetite
* High levels of liquid intake
* Higher frequency of urination
* A gradual degeneration of the nervous system

A series of tests need to be conducted to confirm the presence of Cushing’s disease in dogs. Samples of blood and diluted urine are analyzed to give a preliminary indication. If the disease is suspected, further laboratory tests are performed that can be fairly accurate in diagnosis and can even direct the physician to the root of the problem.

Other endocrinal disorders like diabetes or inflammation of the pancreas tend to appear along with Cushing’s disease. These ailments add to the suffering of the dog and unfortunately reduce the chances of survival.

Sources
http://www.wedgewoodpharmacy.com
http://www.vetinfo.com
http://endocrine.niddk.nih.gov
http://dogs.about.com
http://www.2ndchance.info
http://www.seefido.com
http://www.kateconnick.com

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